Hydrocele can be anti-inflammatory using antibiotic drugs, such as amoxicillin, ofloxacin and other drugs. Amoxicillin is indicated for upper respiratory tract infections due to sensitive bacteria, genitourinary tract infections due to Escherichia coli, soft tissue skin infections, and lower respiratory tract infections. Adverse reactions include nausea and vomiting, rash, asthma, anemia, thrombocytopenia, and so on. Penicillin allergy and positive skin test patients are prohibited. Dosage should be adjusted in the presence of allergic diseases such as asthma and in the elderly, and in the presence of severe renal impairment. Penicillin skin test is required for the use of the drug, and the blood routine and liver and kidney function should be rechecked regularly when the course of treatment is long. Ofloxacin is indicated for genitourinary infections, respiratory tract infections, gastrointestinal tract infections and other conditions. Its adverse reactions include abdominal discomfort, diarrhea, nausea and vomiting, headache, drowsiness, and rash. It is contraindicated in patients who are allergic to fluoroquinolones and in pregnant women. Dosage should be adjusted for renal and hepatic hypoplasia; it is contraindicated in patients under eighteen years of age. In addition, not all hydronephrosis need anti-inflammatory treatment, if there is no co-infection, there is no need for anti-inflammatory treatment, when the symptoms of hydronephrosis are serious, you may also need to choose intravenous injection, surgery and other ways of treatment under the guidance of the doctor. It is recommended that patients with hydronephrosis should consult the doctor in time and follow the doctor’s instructions to carry out scientific and effective treatment. Antibiotics can cause adverse reactions and should be avoided on their own.