If a woman doesn’t get her period without taking progesterone, then consider that it may be related to a lack of luteal function in the body. A woman’s menstruation comes only when estrogen and progesterone interact with each other. If a woman’s corpus luteum is insufficiently functioning, she will not be able to secrete enough progesterone, and thus will not be able to feedback regulation. At this time, the endometrium will not shed, which will lead to a lack of menstruation. After supplementing progesterone, the pituitary LH and FSH secretion will be reduced accordingly, the corpus luteum will start to atrophy, the secretion of estrogen and progesterone will be reduced, and the endometrium will lose the support of sex hormones, and shedding will occur and menstruation will occur. However, it should be noted that progesterone drugs can not be used regularly to avoid hormone dependence. You can check the hormone six levels before using the medication to clarify the cause and then use the medication under the guidance of your doctor.