There is no such thing as intrahepatic bile duct stones in Chinese medicine, but according to its symptoms, it can generally be categorized as “dystocia (pain in the area of coercion and ribs)” and “jaundice”, etc. It is not clear that Gentian Diarrhea Pills can treat intrahepatic bile duct stones. Gentian Diarrhea Pill does not have the effect of treating intrahepatic bile duct stones, but it can alleviate the symptoms of the corresponding diseases caused by liver and gallbladder dampness-heat (dampness-heat evils deposited in the liver and gallbladder), and the disturbance of liver fire. Gentian Diarrhea Pill is composed of gentian, Chaihu, Scutellaria, Gardenia, Zedoaria, Mouton, Psyllium, Angelica and so on. It is effective in clearing the liver and gallbladder and inducing dampness-heat. It is used for dizziness and redness of eyes (dizziness and red eyes) caused by damp-heat of liver and gallbladder (damp-heat evils accumulated in liver and gallbladder), tinnitus and deafness, pain in ears, dystocia and coercive pain and bitterness in the mouth (feeling pain in the area of dystocia and ribcage, and bitterness in the mouth). Use with caution in pregnant women, the elderly and infirm, and those with loose stools. Avoid spicy stimulating food. It is not advisable to take tonic Chinese medicine at the same time while taking the drug. Adverse reactions and contraindications are not clear. The vast majority of intrahepatic choledocholithiasis are found during physical examination, with no obvious symptoms or serious consequences, and generally do not require treatment. When a very few patients develop extensive multiple intrahepatic bile duct stones, resulting in jaundice, liver fibrosis and localized cirrhosis, internal medication or surgical treatment may be required, and a diagnosis and treatment plan should be determined under the guidance of a physician. In summary, gentian liver pill can not directly treat intrahepatic bile duct stones, diagnosed with intrahepatic bile duct stones should follow the doctor’s instructions standardized treatment, do not blindly self-medication.