There are many types of liver and gallbladder diseases, such as cholelithiasis, biliary tract infections, liver cancer, cirrhosis, etc. Possible symptoms or manifestations include right upper abdominal pain, jaundice, manifestations of infections, manifestations of liver insufficiency, and so on. 1. Cholelithiasis: Cholelithiasis includes gallbladder stones and bile duct stones. Most of the patients with gallbladder stones have no obvious symptoms, or only have discomfort in the right upper abdomen. When the stone is embedded in the cystic duct, it can cause biliary colic, which is characterized by paroxysmal pain in the right upper abdomen; bile duct stones can cause obstruction of the common bile duct, and the patient may have jaundice, fever, pain in the right upper abdomen and other manifestations. 2. Biliary tract infection: including acute cholecystitis and cholangitis. Acute cholecystitis mainly manifests as fever with right upper abdominal pain, which is mostly paroxysmal colic; acute cholangitis often has more serious symptoms, and on the basis of fever, jaundice, abdominal pain, shock or even delirium may occur. 3. Hepatocellular carcinoma: patients with hepatocellular carcinoma have no obvious symptoms or performance in the early stage, and when there are obvious symptoms, they are already in the middle or late stage, including discomfort or pain in the liver area, enlarged liver, mass in the right upper abdomen, jaundice, fatigue, emaciation and so on. 4. Cirrhosis: when the symptoms of cirrhosis are obvious, the patient is already in the stage of decompensation, and the patient mainly manifests liver insufficiency and portal hypertension, the former includes maldigestion and absorption, malnutrition, jaundice, bleeding tendency, anemia, endocrine disorders, etc.; the latter is mainly upper gastrointestinal hemorrhage caused by splenomegaly, ascites and rupture of varices in esophagogastric fundus veins and hemorrhage. Patients suspected of having hepatobiliary diseases are recommended to go to the hospital as soon as possible for consultation, so that the diagnosis can be clarified as soon as possible and then treated accordingly.