Indirect bilirubin, also known as unconjugated bilirubin, can be elevated in neonatal jaundice, cirrhosis and other hepatocellular and hemolytic factors. Indirect bilirubin, when elevated to a certain degree, is mainly manifested by yellowing of the sclera, yellowing of the skin, etc. Some patients may be accompanied by nausea, fatigue, loss of appetite, etc., and even itching of the skin. When the patient’s indirect bilirubin is high, it is necessary to have regular checkups, to clarify the cause of bilirubin elevation under the guidance of professional physicians, and to observe the changes in direct bilirubin, indirect bilirubin and total bilirubin, and combine the three to make a diagnosis. If discomfort occurs, it is recommended to consult a doctor immediately for early diagnosis and treatment.