Provided that they are not allergic to cephalosporin, patients with sinusitis can take cephalosporin for treatment under the guidance of a doctor. Cephalosporin can destroy the cell wall of bacteria and sterilize them during the reproduction period, thus sinusitis patients can apply cephalosporin treatment. Most of the pathogenic bacteria causing sinusitis are Streptococcus hemolyticus or Staphylococcus aureus, which are more sensitive to cephalosporins, so the application of cephalosporin for sinusitis will be effective. It is recommended that patients with sinusitis undergo bacterial culture and drug sensitivity tests, and treatment will be more targeted. If the test results show an anaerobic bacterial infection, it is necessary to take metronidazole and other drugs for treatment at the same time. In addition to the application of anti-inflammatory drugs, patients can use decongestants, such as ephedrine, to treat symptoms such as nasal congestion and runny nose, as well as topical glucocorticoid-based nasal sprays. If the symptoms are severe, sinusitis patients can also be treated with sinus endoscopic surgery. Daily saline rinses can be applied to improve the discomfort, and the head can be slightly elevated when sleeping to facilitate nasal drainage and discharge of secretions.