There is no uniform conclusion on how long can one live after surgery for esophageal cancer which is poorly differentiated without metastasis, and its survival period is related to postoperative pathology, treatment effect and patient status. Clinically, the 5-year survival rate is usually used to evaluate the survival time of patients. There is no statistical data on how long the patients can live after surgery for esophageal cancer with low differentiation and no metastasis, the 5-year survival rate after radical esophageal cancer surgery is around 30~40%, and the prognosis of advanced esophageal cancer is even worse, with the median survival time of 6~10 months. Usually, the earlier the cancer is detected, the earlier it is diagnosed, and the earlier the standardized treatment is administered, the better the prognosis is, and the longer the survival time is. After esophageal cancer surgery is low differentiation without metastasis, it is recommended to follow the doctor’s instructions for postoperative treatment and care to strive for a longer life cycle.