The symptoms of lung cancer in the middle and late stages include: hemoptysis. It always accompanies the course of lung cancer and is one of the common first symptoms of lung cancer. The cancerous tissues are rich in blood vessels, so it is often persistent and intermittent to have blood in sputum repeatedly in small amounts, which is not easy to control. Symptoms of shortness of breath. Bronchial stenosis and obstruction cause shortness of breath, which is more often seen in central lung cancer. When enlarged lymph nodes compress large bronchus or bulge, or when alveolar cancer spreads widely, shortness of breath will be progressively aggravated and accompanied by cyanosis. Severe shortness of breath can occur in large pleural effusion and pericardial effusion, etc. Severe pain in the chest. If the tumor involves the pleura or mediastinum, it may produce irregular dull pain or hidden pain in the chest. If the tumor erodes the ribs of chest wall or presses the intercostal nerve, the chest pain will be sharp and severe with fixed point or local pressure pain, and it will worsen with breathing, coughing and changing position. The cough is severe. About 3/4 of patients present with varying degrees of coughing. It is characterized by paroxysmal irritating cough mainly, without sputum or a small amount of foamy white sputum. The cough is aggravated by bronchial stenosis caused by tumor enlargement, and is mostly persistent with a high-pitched metallic sound. When there is secondary infection in the lung distal to the bronchial stenosis, the sputum volume increases and it is mucopurulent sputum. Fever symptoms. In the middle stage of lung cancer, fever is caused by obstructive pneumonia, and the symptoms can be relieved after antibiotic treatment. Most of the patients are accompanied by night sweats, dry mouth, heartburn, hand and foot fever and other symptoms.