Sigmoid colon cancer T4N0M0 is a clinical TNM staging for sigmoid colon cancer lesion, and the corresponding staging refers to the lesion belonging to the middle stage. Sigmoid colon cancer T4N0M0 means that the primary lesion has penetrated the whole layer of sigmoid colon, partially invaded the surrounding tissues and organs, and there is no regional lymph node metastasis or distant organ metastasis. The overall clinical staging of the tumor belongs to stage IIB to IIC, which is an intermediate stage. The corresponding lesion requires preoperative and postoperative adjuvant radiotherapy and radical surgical resection. If the corresponding stage of sigmoid colon cancer is detected through examination, it is necessary to consult a doctor in time and carry out standardized treatment under the evaluation and guidance of clinicians, so as to avoid delaying the aggravation of the disease and affecting the prognosis of survival.