Pathologically elevated alkaline phosphatase can be seen in bone diseases such as rickets, bone malignancy, and bone metastasis of malignant tumors; liver and gallbladder diseases such as extrahepatic bile duct obstruction, hepatocellular carcinoma, and cirrhosis; and other diseases such as hyperparathyroidism. High alkaline phosphatase should be treated according to different causes. 1 Calcium supplement: high alkaline phosphatase caused by rickets due to calcium deficiency can be treated by taking calcium carbonate, calcium gluconate, vitamin D and other medicines, and foods containing high calcium such as shrimp, eggs, fish and lean meat should be consumed in normal life. 2. Treatment of primary diseases: high alkaline phosphatase caused by liver and gallbladder diseases can be treated by taking medicines such as hepatoprotective tablets and compound glycyrrhizin tablets, which can improve the abnormal liver function and promote the proliferation of liver cells. 3. Immune system disorders: high alkaline phosphatase caused by immune system disorders can be treated by taking drugs such as atilizumab and divalizumab, which can activate the autoimmune system and establish targeted defense mechanisms. When the alkaline phosphatase is high, it is recommended to go to the hospital for timely consultation, to clarify the cause of the disease and timely symptomatic treatment.