The scientific name for cross-eye is entropion. Baby entropion can be treated by correcting refractive error, bifocal glasses, prism therapy, treating amblyopia, and extraocular muscle surgery. Esotropia is a convergent misalignment of the visual axis. Treatment of esotropia includes correction of refractive error, bifocal glasses, prism therapy, treatment of amblyopia, extraocular muscle surgery, and botulinum toxin injections. Correction of refractive error is the primary treatment modality, which involves the use of prescription eyeglasses; bifocal glasses are more appropriate for patients with potential for sensory fusion; prism therapy is less commonly used and is generally used as an adjunct; treatment of amblyopia is generally initiated prior to strabismus surgery to improve surgical success; and extraocular muscle surgery is generally employed when previous treatments have not been effective. Botulinum toxin injections, which chemically denervate the eye and cause temporary muscle weakness, are an alternative to surgery, but the therapeutic value has not been clarified, and there are more side effects, such as perforation of the eye and medically induced ptosis. Clinical use of cholinesterase inhibitors such as iodophorin will also be used to treat internal strabismus, but long-term use is not as good as corrective lenses, and may also have systemic adverse side effects. It is recommended that babies with crossed eyes should go to a regular hospital in time, and follow the doctor’s instructions for symptomatic treatment.