There is no such thing as a quick relief for headaches the day after drinking, and the treatment should be based on the cause of the patient’s headache. A headache after drinking may be caused by the action of alcohol on the human body, and may be caused by the induction of migraines after drinking, or may be caused by methanol poisoning, which is caused by different reasons and different treatment methods. 1. Acute alcohol poisoning: Acute alcohol poisoning can lead to symptoms of headache the next day after drinking alcohol, treatment should promote alcohol metabolism, can use Metadoxine, in addition, can also use naloxone and other drugs for treatment. 2. Migraine: If drinking alcohol induces a migraine, it can also lead to headaches the next day after drinking alcohol, the treatment should be careful to use aspirin and other drugs, can be more water to promote the metabolism of alcohol in the body, but also through physical therapy and other ways to treat. 3. Methanol poisoning: drinking poor quality fake wine can lead to methanol poisoning, methanol poisoning can also lead to the symptoms of headache the next day after drinking wine, the treatment can use methyl pyrazole detoxification, but also through the blood purification dialysis to assist the methanol metabolism. In addition to the above factors, other factors can also lead to the symptoms of headache the next day after drinking alcohol, it is recommended to consult a doctor in a timely manner to identify the causes and ask the doctor to deal with it.