Urine routine examination shows two plus signs of urine occult blood, then there may be urinary system bleeding disease, need further examination to clarify the specific cause. 1, the occurrence of urinary system infection can appear two plus signs of occult blood, mostly accompanied by urinary frequency, urinary urgency, painful urination and other symptoms, in addition to urine occult blood positive performance may also be accompanied by an increase in the number of white blood cells, an increase in the number of bacteria, etc., need further analysis to identify; 2, the occurrence of urinary system Stones, such as kidney stones, ureteral stones and bladder stones, may show two plus signs of urine occult blood, which is detected when blood is mixed in the urine due to the damage to the surrounding mucous membrane caused by stones, usually accompanied by pain in the lower back and abdomen, which needs to be further identified by urinary ultrasound; 3, urinary tumors, which destroy the mucous membrane and bleed, resulting in blood mixed with urine, which is positive for occult blood and needs to be further identified by urinary ultrasound or CT. The diagnosis should be confirmed by ultrasound or CT examination of the urinary system.