Tetanus prophylaxis is usually 1 injection. Special cases (e.g. drug allergy, severe trauma, people at high risk of trauma, prophylactic vaccination, etc.) require multiple injections or higher doses according to the schedule. Tetanus that is, tetanus antitoxin, skin test is required before injection; skin test negative, usually a one-time injection of 1500 units, 1 injection can be; and skin test positive need to be used to desensitize the injection, 1 tetanus antitoxin injected in 3 times, need to be injected 3 injections. Deep wounds with much mud, rust and other dirt have a high risk of Clostridium tetani infection. Skin test and prophylactic injection of tetanus are feasible with local injection of tetanus antitoxin around the wound after thorough debridement; clinical treatment of tetanus can be used up to 150,000 to 200,000 units of tetanus antitoxin or more. Trauma high-risk risk groups may be more traumatic, pre-exposure use of the need for full immunization: the first year of vaccination injection twice, the second year of injection, the immune cycle up to 5 to 10 years, strengthen immunization is generally every 10 years and then injected. China’s children’s immunization program tetanus is not a separate injection, generally with diphtheria, pertussis and other multiple vaccine co-injection, respectively, 3 months after birth, 4 months, 5 months, 18 months and 6 years of age when each inoculation, a total of five injections. Trauma should be regulated in time to seek medical treatment, wound cleaning, vaccination, etc. need to follow the physician’s advice to implement, so as to avoid carelessness caused by the great harm.