Lyme disease is a naturally occurring disease transmitted by Borrelia burgdorferi through the bite of a hard tick. The main infectious agents of Lyme disease are mainly the black-lined chinchilla, dahlin chinchilla, yellow rat, brown house mouse, etc. It can be transmitted through the bite of ticks on humans. The incubation period of Lyme disease is usually 3 to 32 days, with an average of 7 days. Clinically, Lyme disease is characterized by fever, headache, malaise, chronic erythema, arthritis, cardiac abnormalities, neurological and other multi-organ and multi-system damage. Once diagnosed with Lyme disease need to apply antibacterial drug treatment early, the treatment is mainly for the spirochete to treat, including doxycycline, amoxicillin and other drugs can be effective treatment of Lyme disease. Patients with Lyme disease, once diagnosed, need to be treated as soon as possible, and the prognosis is usually good. The prognosis is usually good. If there is severe damage to the central nervous system, it can lead to serious sequelae.