Hepatitis B (referred to as hepatitis B) “trilogy”, refers to the existence of hepatitis B with chronic hepatitis cirrhosis liver cancer course transformation. How to block the transition of chronic hepatitis to cirrhosis and hepatocellular carcinoma is an important symbol of the success of hepatitis B treatment. At present, there is a lack of effective treatment for hepatitis B, but regular examination is very necessary. Generally speaking, chronic carriers should check liver function once every three months, and check “two half” and “ultrasound”, HBVDNA, alpha-fetoprotein and liver fibrosis index once every six months. Patients with active liver disease should check the relevant items at any time according to the needs of their condition. At present, there are a lot of drugs for liver disease treatment, and various advertisements are endless. In fact, there is no specific treatment for liver disease, and the key lies in systematic and regular treatment. It is necessary to ensure the course of treatment and gradually withdraw the drugs, but also according to the condition and course of the disease, to take long-term phased treatment. Therefore, the combination of Chinese and Western medicine can often complement each other’s strengths and improve the efficacy of treatment. 1.Antiviral treatment should grasp the timing: when antiviral treatment, it can be considered to cooperate with immunomodulators or traditional Chinese medicine to identify and treat, in order to enhance the therapeutic effect. 2.Anti-liver fibrosis is mainly based on traditional Chinese medicine: liver fibrosis is the bridge of transition from chronic hepatitis to cirrhosis. Treatment should be based on traditional Chinese medicine. 3, comprehensive prevention and treatment of precancerous liver lesions: from the viewpoint of Chinese medicine theory, no matter liver fibrosis, cirrhosis or liver cancer, they are all blockage of liver blood, and should be treated by activating blood circulation and removing blood stasis, the difference is the degree of difference, and the application of medicines differ, and according to the situation of detoxification, benefiting the qi, dispelling dampness, eliminating the conductor. Third, pay attention to the maintenance of hepatitis B, “three parts treatment, seven parts maintenance”. ① active period to bed rest, stable period is a combination of work and rest; ② to light and nutritious food, avoid alcohol; ③ to maintain mental harmony, avoid emotional fluctuations; ④ simple medication, avoid contact with and use of liver-damaging drugs and chemical carcinogens.