Syphilis is usually treated with long-acting penicillin by intramuscular injection, and other medications may be taken orally for those who are allergic to penicillin. The preferred option for syphilis treatment is intramuscular long-acting penicillin. As some people are allergic to penicillin and should not be treated with penicillin, they can be treated with ceftriaxone injections, oral doxycycline and other medications under the guidance of a doctor. Due to the different stages of syphilis, the treatment program is also different. Once diagnosed, you should cooperate with your doctor to choose the appropriate treatment plan and actively treat the disease so as to achieve a good therapeutic effect. Syphilis patients due to individual differences, so there is no most effective drugs, patients need to actively seek medical treatment. At the same time should maintain good habits, pay attention to personal hygiene, good isolation measures to prevent the spread of the disease.