Patients in coma sometimes have hypoxemia, and long-term hypoxemia can cause damage to the heart, brain and kidneys, so oxygen can avoid damage to the above-mentioned vital organs. At the same time, patients should improve the relevant examination to clarify the cause of coma and make appropriate treatment. If the patient is in coma due to pulmonary encephalopathy, the patient should be treated with a non-invasive ventilator or an invasive ventilator as needed. For example, if the patient has pulmonary encephalopathy due to chronic obstructive pulmonary disease, anti-infection, expectorant and asthma treatment should be given according to the condition. If the patient is in coma due to cerebrovascular disease, appropriate treatment should be given and attention should be paid to prevent complications.