The pain and itching at the connection between the pubic area and the anus may be caused by pubic eczema, inflammation of the pubic area, pinworms, etc., which can be treated with medications. 1. Pubic eczema: when the pubic area suffers from eczema, the patient will have the symptom of itching in the anus as well as around the pubic area, and the patient can use tretinoin econazole cream, compound dexamethasone cream and other treatments to alleviate the symptoms of pain and itching. 2. Inflammation of the pubic area: If there is an inflammatory reaction in the pubic area, the patient may also have the manifestation of pain and itching in the connection between the pubic area and the anus, which can be treated with Clindamycin Hydrochloride Cream, Mupirocin Ointment and so on. 3. Pinworms: If you suffer from pinworms, you will mainly have itching around the anus, which will be aggravated at night, and the itching may spread to the connection with the pubic area. Patients can be treated with aminomercuric oxide ointment and pinworm ointment. It is recommended that patients with the above situation to consult a doctor in a timely manner, under the guidance of a professional doctor to clarify the cause of the disease, give the appropriate medication for treatment, and follow the doctor’s instructions to use.