The first and fifth positive hepatitis B tests mainly indicate that the human body is infected with the hepatitis B virus. Hepatitis B five is one of the main methods to screen whether you have hepatitis B virus in clinic, the first and fifth positive means hepatitis B surface antigen and core antibody are positive, hepatitis B surface antigen is positive indicates that the human body is infected with hepatitis B virus, hepatitis B core antibody is positive indicates that the human body has been infected with hepatitis B virus in the past or in the recent past, when both are positive at the same time, it means that the human body is carrying hepatitis B virus. It is recommended that patients who are positive for the first and fifth items of hepatitis B virus should be further examined for the quantification of hepatitis B virus DNA and liver function, if there is no abnormal liver function or histological damage of the liver, then they are hepatitis B small two-positive carriers and do not need to be treated. If there is liver function abnormality or liver damage, antiviral treatment is needed. During the treatment period, avoid spicy and stimulating food in the diet, and focus on light, nutritious and easy to digest. Those with abnormal results of hepatitis B five tests are recommended to consult a hepatologist for further diagnosis and treatment.