Symptoms that may appear 15 days before the terminal stage of cancer include severe pain, severe weight loss, generalized swelling, mental symptoms and so on. 1. Severe pain: most of the advanced cancer patients have different degrees of cancer pain, especially those who have bone metastasis or tumor invasion and compression of large nerves. 2. Severe wasting: most of the advanced cancer patients have serious eating disorder and serious malnutrition. And malignant tumor itself is a consumptive disease, so cancer patients will show severe wasting or even malignant disease before death. 3. Generalized edema: cardiac and renal failure, severe malnutrition, tumor invasion and so on can cause tissue edema, which is manifested as generalized edema in serious cases. In addition, when the tumor invades the pleura or peritoneum, a large amount of pleural effusion or ascites will be formed. 4. Mental symptoms: due to long-term disease torture, persistent severe pain, organ failure, etc., patients with advanced cancer will have different degrees of mental abnormalities, such as indifference, agitation, delirium, drowsiness, coma and death. When cancer appears, it is necessary to actively carry out treatment under the guidance of physicians to prolong the survival period of patients.