Many people may experience back pain after a fever for complex reasons. Sometimes it can be understood that after the fever has gone down, the body is in a weaker state, which is prone to aseptic inflammation, and aseptic inflammation is not the same as inflammation of the throat. Inflammation of the throat may be a bacterial infection, to be treated with antibiotics such as cephalosporin, penicillin. Aseptic inflammation, on the other hand, can be caused by cold, fatigue, trauma, over-activity, and physical weakness. They can be relieved with rest or symptomatic treatment. Fever will be reduced, after the fever is reduced, the body’s resistance is relatively weak, easy to induce aseptic inflammation, which is the most common situation, so the cause of back pain after the fever is reduced, most of the reasons can be attributed to aseptic inflammation. However, to exclude other rare cases, especially fever-related diseases can cause back pain, which must be combined with clinical history and physical examination, as well as the necessary laboratory tests, as well as imaging tests to determine, try not to cause unnecessary damage to the patient because of misdiagnosis or omission of diagnosis.