The mucous membrane of the rectum has a certain absorptive capacity for drugs, so in the case of oral medication is limited, you can choose to insert antipyretic drugs from the anus for antipyretic treatment. The adverse reaction of this type of drug delivery is relatively small, mainly will produce local stimulation, such as in the process of drug delivery, the surrounding mucous membrane damage, or in the process of drug absorption, the mucous membrane around the absorption of the drug has irritating changes, usually in the cessation of the drug for a day or so, the symptoms can be gradually recovered. However, if the adverse reaction is induced by allergy, anti-allergy treatment is required.