There is no fastest and most effective treatment for severe hair loss. Generally, it is necessary to target the cause of the disease and reasonably choose medication, surgery and other ways of treatment. Generally, the amount of hair loss per day is less than 100, which is a physiological phenomenon, if the hair loss is more than one hundred per day, it is considered to be androgenetic alopecia, baldness and so on. 1. Physiological factors: normal people will have a certain amount of hair loss every day, as long as the amount of hair loss is not more than 100 per day, it is a normal phenomenon, and does not require special treatment. It can be adjusted by paying more attention to rest and eating a balanced diet. 2. Pathological factors (1) Androgenetic alopecia: after the diagnosis of this disease, for male patients, oral finasteride can be used to inhibit type II 5α-reductase, inhibit the conversion of testosterone to DHT, thus reducing the destruction of hair follicles; for female patients, oral ethinyl estradiol, cyproterone and spironolactone can be used for treatment; topical minoxidil application can be used to promote the growth of hairs; and hair transplantation can be used for treatment if necessary. (2) Patchy baldness: for small patchy baldness, topical glucocorticoid treatment, such as halometasone, mometasone furoate, etc.; topical minoxidil can also be used to dilate blood vessels and promote hair growth; for children with serious condition or long duration of the disease, topical anthralin can be used for treatment; for cases of rapid progress of the disease, oral glucocorticoid treatment, such as prednisone, etc., is available. For children with rapid progression of the disease, oral glucocorticosteroid therapy can be given, such as prednisone, etc. It is recommended that patients according to their own situation, if it is caused by disease factors, need to go to the regular hospital dermatology department, follow the doctor’s instructions for treatment, the use of drugs, need to strictly follow the doctor’s instructions for medication, can not blindly self-medication, to avoid adverse reactions.