Urine albumin creatinine ratio is the ratio of albumin to creatinine in urine, which is related to 24-hour urine protein excretion and urine micro-protein excretion rate. Because of the high sensitivity of this index and the convenience of specimen retention, this index is commonly used in clinics to determine early kidney damage such as early glomerulonephritis, diabetic nephropathy, hypertensive nephropathy and so on. Under normal circumstances, albumin is almost reabsorbed in the kidney and does not appear in the urine. When there is damage to the glomerular filtration membrane, the albumin filtered out from the glomerular filtration membrane exceeds the reabsorption function of the kidney, then albumin will appear in the urine. Creatinine, on the other hand, is not absorbed as it passes through the kidneys and is excreted in its entirety, so renal function can be observed by combining the two. The normal albumin creatinine ratio should be less than 30mg/g. If the ratio is 30-300mg/g, it means that a small amount of proteinuria is present, and if it is more than 300mg/g, it means that a large amount of proteinuria is present. The larger this ratio is, the more albumin is filtered through the kidneys, thus indicating that the kidneys are more severely damaged. Because of the high sensitivity of this indicator and the convenience of specimen retention, it is commonly used in the clinic to determine the early stage of renal damage, such as the early stage of glomerulonephritis, diabetic nephropathy, hypertensive nephropathy and so on. If you have an abnormal urine albumin to creatinine ratio, you should consult a regular hospital in time and complete the relevant examinations under the guidance of a physician to clarify your condition and carry out targeted treatment.