High total bile acid after cholecystectomy may be caused by physiologic factors, hepatitis or bile duct stones. 1. Physiological factors: total bile acid can be elevated in the short term after cholecystectomy, which can be caused by a full meal, consuming too much food with high fat content or pregnancy. 2. Hepatitis: patients after cholecystectomy may also have hepatitis, which will destroy liver cells, leading to a decrease in the liver’s ability to metabolize bile acids, resulting in the reflux of total bile acids into the bloodstream, resulting in an increase in total bile acids. 3. Biliary stones: biliary stones occur after gallbladder removal, biliary stones will block the bile ducts, resulting in total bile acid discharge pathway is blocked, causing total bile acid reflux, resulting in total bile acid elevation. High total bile acid after cholecystectomy may also be due to other reasons, you should go to the hospital in time to improve the examination, to clarify the cause of the disease and then give targeted treatment.