Insomnia symptoms after cholecystectomy are not obviously related to the removal of the gallbladder, and may be caused by the patient’s excessive mental stress. Patients can relieve the symptoms through medication and psychological counseling. 1. Medication: Insomnia caused by cholecystectomy belongs to the insomnia caused by autonomic nerve dysfunction and heart and gallbladder deficiency, and can be relieved by taking medications that regulate the nerves, such as eszopiclone and ghrelin. 2. Psychological guidance: patients after cholecystectomy is in the recovery period, patients due to worry about the condition, mental stress caused by insomnia, to learn to regulate their own emotions, try to maintain a positive and optimistic attitude, while you can assist some of the activities such as distraction, relaxation of the body and mind, will help the condition to recover. After cholecystectomy, patients should avoid exertion, ensure sufficient sleep and rest time, which will help the recovery of the condition, if there is any discomfort, please consult the doctor in time.