Bile duct adenocarcinoma belongs to cancers with higher malignancy, but early and active treatment can achieve better results. Cholangiocarcinoma refers to malignant tumors occurring in the extrahepatic bile ducts, i.e. the left and right hepatic ducts to the lower end of the common bile duct. More than 95% of the histologic types are adenocarcinoma. If there is no spread and metastasis in early-stage patients, through radical surgical resection, patients can get better results and have the possibility of cure. For advanced cases that cannot be resected, percutaneous hepatic perforation of the bile ducts for drainage, placement of biliary stent or gastrojejunostomy should be performed, which is a palliative treatment and the therapeutic effect is far less than that of early stage. If you have bile duct adenocarcinoma, you should seek medical treatment in time. Early treatment is still effective, and you should actively cooperate with doctors for treatment. After surgery, one should follow the doctor’s instruction for regular review to avoid recurrence.