The generic name of Mamia is Bacillus subtilis Duplex, which contains two kinds of live bacteria, Bacillus subtilis and Enterococcus, and is mainly used clinically for the treatment and prevention of gastrointestinal diseases such as enteritis and diarrhea. Since it is a live bacteria preparation, if the concentration of stomach acid in the stomach is too high before meal, it will easily kill the live bacteria in it and reduce the therapeutic effect, if there is difficulty in swallowing, the drug can be dissolved in warm water or milk and taken. But do not use hot water with high temperature, if the water temperature exceeds 40 ℃ may kill the live bacteria inside and affect the therapeutic effect. Patients who are also taking antibiotics or proprietary Chinese medicines containing alcohol should also take Bacillus subtilis diphtheriae at least 2 hours after taking the medicine.