A variety of factors can lead to the development of polygenic premature atrial contractions, and the severity usually depends on whether or not the patient has developed organic heart disease. If the patient is suffering from physiological factors, such as stress and anxiety, the occurrence of multiple atrial premature beats is not a serious condition. However, if the patient is suffering from organic heart disease, such as coronary heart disease, hypertensive heart disease, cardiomyopathy, rheumatic heart disease, mitral valve prolapse, etc., the multiple atrial premature beats are usually relatively serious, which means that there will be 5 or more ventricular premature beats per minute, and these conditions will also lead to the patient’s electrocardiogram changes with different waveforms. This condition must be treated aggressively, otherwise it can lead to obvious dystonic or ternary rhythms, etc., and the patient will have malignant arrhythmia, causing cardiogenic shock.