The difference between eczema and herpes mainly includes etiology, clinical manifestations, treatment and other aspects. 1. Etiology: eczema is an inflammatory skin lesion caused by a variety of internal and external factors, and internal stimuli such as mental factors, immune factors, infected foci, endocrine disorders, chronic gastroenteritis, etc.; external stimuli, such as chemicals, sun exposure, animal fur, climate, living environment and many other factors. Herpes is caused by herpes simplex virus, varicella-zoster virus and other infections. 2. Clinical manifestations: eczema can be divided into acute eczema, subacute eczema, chronic eczema and so on. The skin lesions are polymorphic, can be manifested as erythema, papules, blisters, mossy changes, etc., self-conscious intense itching. Herpes usually manifests as clusters of blisters on the basis of erythema, and the symptoms are mainly painful. 3. Treatment: The treatment of eczema should pay attention to avoid irritating factors. Commonly used drugs are topical glucocorticoid drugs, calcium-modulated neurophosphatase inhibitors and so on. For herpes treatment for antiviral therapy, commonly used drugs are acyclovir, vasiclovir, etc., can be oral or topical combination. Whether you are suffering from eczema or herpes, you should follow the doctor’s instructions to use medication, not blindly use medication on your own. Daily skin care should be done to keep the skin clean.