Topical time-delay sprays are generally used to prolong sexual life, and their hazards include causing female frigidity, male erectile difficulties, and allergies. It is recommended that patients use caution and follow the doctor’s instructions for external use. 1. cause female frigidity: delay spray cleaning time is not thorough, couples live with pharmaceutical residues may enter the vagina, the female vagina will be paralyzed symptoms, the ability to vaginal stimulation will be reduced, over time women may appear frigid situation. 2. male erection difficulties: the main principle of the current delay spray is to make the glans less sensitive. If the amount of these drugs before sex is too large, the epidermal nerves of the glans will be completely paralyzed, so that it can not feel the external stimuli, and thus can not be communicated to the sexual center of the cerebral cortex, which will further lead to the inability to get an erection. 3. Allergy: some patients may be allergic to the components of the delay spray, resulting in itching, redness and swelling of the skin and other symptoms. There are other hazards of delay sprays, and patients are advised to use delay sprays under the guidance of a doctor.