Anal papilloma is a benign tumor, early removal basically will not be cancerous. However, letting anal papilloma develop, and long-term friction, inflammation and other stimuli will lead to anal papilloma cancer. Due to long-term friction and stimulation of the anal papilla, resulting in anal papilloma hyperplasia and enlargement, if not treated in time, repeated prolapse outside the anus, anal papilloma friction and so on will be greater, with the passage of time anal papilloma can be cancerous. Bacterial infections and injuries may cause inflammation of anal papilloma and the inflammatory hyperplasia, and long-term infection and inflammation will lead to cancerous cells, which will evolve into cancerous anal papilloma. It is recommended to keep the bowel movement smooth, pay attention to anal hygiene, avoid bacterial infection can avoid the occurrence of anal papilloma. However, when anal papilloma is found, it must be handled in time according to the doctor’s prescription, and regular checkups should be conducted to avoid cancerous changes.