What is gouty arthritis?

  Gout is a disorder of uric acid metabolism characterized by increased uric acid in blood and body fluids and deposition of urate in tissues, causing an inflammatory response, which can lead to gouty arthritis when joints and their surrounding tissues are involved. The early stage of the disease is characterized by swelling of the soft tissues around the joints without bone destruction, and as the disease progresses, bone and cartilage destruction and gouty nodules appear. Bone destruction is typically characterized by small capsular or chisel-like round or oval defects with sharp edges at the joint ends, with normal bone density and structure around the lesion and no osteoporosis. The lesions often involve the small joints of the hands and feet, especially the first metatarsophalangeal joint, and then gradually invade the wrist, ankle, elbow and other joints.