Examination of the bile, liver, spleen and pancreas does not show any abnormality, it does not exclude the possibility of gastric ulcer, gastric ulcer needs to be combined with the symptoms, gastroscopy and other diagnostic. Gastric ulcer is a localized inflammatory defect of gastric mucosa caused by erosion of gastric acid and pepsin. Gastric ulcers usually do not attack other organs, and the absence of significant abnormalities in the biliary, liver, pancreatic, and splenic organs does not mean that gastric ulcers do not exist. The occurrence of gastric ulcer has correlation with Helicobacter pylori infection, drugs and so on. Typical clinical manifestations of gastric ulcers include postprandial epigastric pain, acid reflux, abdominal distension, belching, and so on. A history of medication use, such as non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin, is required for diagnosis. Commonly used tests include carbon 14 breath test and gastroscopy to detect H. pylori infection and microscopic observation of gastric mucosal changes. Diagnosis of the disease needs to be carried out by a specialized doctor, and prompt medical attention is recommended.