There is no so-called best way to calm the cough, patients need to be treated according to the cause of the disease, the common factors that cause cough and asthma, including chronic obstructive pulmonary disease, asthma, heart failure and so on. 1. Chronic obstructive pulmonary disease (COPD): due to limited ventilation of the lungs, symptoms of cough and asthma often occur, and cough and asthma are often induced by infection, patients can use cefoperazone sulbactam and other drugs for anti-infective treatment, in addition to the use of aminophylline and other drugs to stop coughing and asthma, and patients need to be long-term use of bronchodilators such as Formoterol budesonide and other drugs to control the symptoms. 2. Asthma: due to the spasm of the airway will also appear symptoms of cough and asthma, the patient can use β2 agonists to relieve symptoms, common drugs including salbutamol, etc., in addition, the patient can use glucocorticoids to control the recurrence of symptoms, the main drugs include inhalation budesonide. 3. Heart failure: heart failure patients due to cardiac insufficiency, will lead to the occurrence of pulmonary stasis, at this time the patient will have symptoms of coughing and wheezing, can be applied to furosemide and other diuretic drugs to reduce sodium retention, at the same time you can use the sakubutra valdecoxib, dagliflozin, metoprolol and other drugs to inhibit cardiac ventricular remodeling, can be effective in improving the symptoms. Coughing and wheezing patients need to consult a doctor in a timely manner to clarify the cause of the targeted treatment to prevent further aggravation of the disease.