Bile reflux with celiac disease is possible to cause back pain. Due to the reflux of bile into the stomach, coupled with excessive gastric acid, it will cause double stimulation to the gastric mucosa, thus causing the condition of gastric mucosal erosion. Patients usually experience abdominal fullness and a persistent burning sensation in the middle and upper abdomen, while some patients may radiate to the chest and back, causing tugging pain in the back, thus bile reflux with celiac disease may cause back pain. Patients can take proton pump inhibitor drugs under the guidance of the doctor for relief, commonly used drugs such as omeprazole, pantoprazole, etc., and can also take oral drugs to promote gastrointestinal peristalsis such as domperidone tablets, mosapride citrate tablets, etc., to promote digestion and reduce reflux. It is recommended that patients with symptoms of bile reflux with celiac disease should first go to the hospital for examination, according to the condition now appropriate treatment, do not delay to avoid aggravation of the condition.