Lymph node enlargement can be caused by infection, tumor, reactive hyperplasia, etc. There is no quick way to reduce swelling, and treatment should be based on the cause. 1. Infections: for various inflammatory infections, such as acute upper respiratory tract infections and other bacterial infections, antibiotics such as cefaclor and amoxicillin can be used for treatment; for Mycobacterium tuberculosis infections, anti-tuberculosis drugs such as isoniazid and rifampicin can be used in combination for treatment. 2. Tumor: those caused by lymphoma can be treated with drugs such as doxorubicin and vincristine, or undergo bone marrow transplantation and other treatments. Lymph node metastasis of other tumors can be treated by surgery, and 5-FU, mitomycin, cisplatin and other chemotherapeutic drugs can be used after surgery. 3. Reactive hyperplasia: if caused by systemic lupus erythematosus and other rheumatic immune diseases, glucocorticoids such as prednisone, methotrexate, interferon and other immunosuppressant drugs can be applied appropriately for treatment. Lymph node enlargement should be timely diagnosis and treatment, and follow the doctor’s instructions for medication.