There are also side effects after progesterone is inserted into the vagina, which are basically similar to those of oral progesterone. Because progesterone is also absorbed into the body through the vaginal mucosa, the following side effects may occur: 1. dizziness may occur, it is best to insert progesterone before going to bed, and then go straight to sleep to avoid dizziness. 2. nausea, regurgitation or anorexia may occur. 3. weakness and drowsiness may occur. Do not be nervous about the side effects. It is recommended to wash the vulva before inserting the medication to avoid pathogenic bacteria entering the vagina together with the medication and causing inflammatory reactions, and the medication should be given only under the guidance of a doctor.