Progesterone is usually absorbed in about two hours after its insertion. Progesterone preparations commonly used for vaginal administration are progesterone vaginal delayed-release gel and progesterone micronized capsules, which are used vaginally to increase the concentration of progesterone in the cervix and uterus. Progesterone inhibits uterine contractions and facilitates the development of the embryo and fetus thus providing a fetal preservation effect. Especially after IVF transfer, the progesterone in the body is relatively slow to rise, so in order to ensure better fetal implantation and development, vaginal administration with oral or intramuscular injection of progesterone is often chosen for fetal preservation treatment. However, after the progesterone melts, some of the residual fluid will be discharged with vaginal secretions, causing increased vaginal discharge and itching of the vulva, so it is necessary to pay attention to the washing of the vulva.