Statins can also be taken by people over 80 years of age as long as there are appropriate conditions, no contraindications, and relative tolerance to adverse effects. Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibiting drugs, which are more efficient and comprehensive lipid-lowering drugs, commonly used drugs include simvastatin, atorvastatin, etc. Statins can lower total cholesterol, LDL and triglycerides. Statins can lower total cholesterol, LDL and triglyceride levels, stabilize and reduce arterial plaque formation. There are numerous statins, and the main contraindications include prohibition of statins in people who are allergic to their ingredients; prohibition of statins in the presence of active hepatitis or unexplained persistent serum transaminase elevations; and contraindication of statins in combination with medications such as the tetralin-based calcium channel blocker mibefradil. Adverse reactions such as abdominal pain, constipation, flatulence, fatigue, weakness, headache, muscle cramps, myalgia, and pancreatitis may occur after taking statins. When the elderly over 80 years of age meet the therapeutic indications of statins and have no relevant contraindications, they can take statins, and the specific medication should follow the doctor’s instructions. Enhance the monitoring of liver and kidney function in the course of medication.