Normal moderate consumption is usually not harmful to the kidneys, long-term consumption of large quantities of protein powder may hurt the kidneys. As protein powder is mainly a powdery substance made from plant proteins extracted from soybeans, milk and dairy proteins. It is mainly suitable for sports exercise, need to increase the muscle of the crowd. Normal moderate consumption usually will not hurt the kidneys. However, if excessive protein is consumed for a long period of time, the protein that cannot be absorbed by the body may be broken down by the liver into nitrogenous substances such as urea, creatinine and ammonia. And these substances need to be excreted through the kidneys, if these substances are too much in the body, it may increase the burden on the kidneys and make the kidneys damaged. So eating protein powder in large quantities for a long time may hurt the kidneys. Protein powder is not suitable to be consumed in large quantities for patients with poor kidney function or some kidney diseases to avoid aggravating the burden on the kidneys, which is not conducive to the treatment and prognosis of kidney diseases. Patients with kidney disease should consult regular hospitals and choose suitable drugs for treatment under the guidance of doctors.