Poor appetite after chemotherapy for esophageal cancer is considered to be the side effect of chemotherapy on the damage of gastrointestinal function as well as the difficulty in swallowing caused by esophageal tumor. It can be improved by adjusting diet, enhancing exercise and medication. 1. Adjusting diet: esophageal cancer patients are weak after chemotherapy, so they need to eat food with high calorie, rich in high quality protein and easy to digest to promote body recovery. If patients have poor appetite, they can try to make their favorite taste and eat small amount of food several times, but they should avoid spicy, greasy and hard food. Patients who have difficulty in swallowing can eat liquid food. 2. Enhance exercise: patients with esophageal cancer who are weak after chemotherapy can do walking, gymnastics, tai chi and other low-intensity physical exercises to enhance physical fitness, promote gastrointestinal peristalsis and improve appetite. 3. Drug regulation: if the appetite is poor after chemotherapy for esophageal cancer, patients can take some drugs to enhance appetite and improve gastrointestinal power, such as Bifidobacterium capsule and Mosapride. Poor appetite after chemotherapy for esophageal cancer requires standardized treatment under doctor’s guidance, avoiding blind medication.