Stomach pain and vomiting may be related to acute gastroenteritis, peptic ulcer, gastric cancer, etc. It can be treated with medication such as omeprazole, domperidone, etc. or surgery. 1. Acute gastroenteritis: mainly caused by unclean diet, mostly manifested as abdominal pain, diarrhea, nausea, vomiting and so on. Patients can take gentamicin, norfloxacin and other antibiotics, or take pantoprazole, omeprazole and other acid inhibitors, as well as magnesium aluminum carbonate and other gastric mucosa protection drugs. 2. Peptic ulcer: including gastric ulcer, duodenal ulcer, mostly manifested as diarrhea, abdominal pain, loss of appetite, nausea, vomiting, etc., and the pain is characterized by periodicity and rhythm. Acid-suppressing drugs such as rabeprazole and omeprazole, prokinetic drugs such as domperidone and gastric mucosa protecting drugs such as bismuth potassium citrate can be taken. 3. Gastric cancer: it refers to cancer originated from epithelial cells of gastric mucosa. Early stage usually has no obvious symptoms, while patients with progressive or terminal stage may have obvious symptoms such as abdominal pain, vomiting, anemia, anorexia and emaciation, etc. The main treatment is to remove the lesion through surgery. Surgery is the main treatment to remove the lesions, sometimes supplemented by radiotherapy and chemotherapy. In addition, severe stomach pain can also take scopolamine and other antispasmodic painkillers, but usually not recommended before the identification of the cause of the disease, to avoid masking the symptoms, affecting the diagnosis. There are many other causes of stomach pain and vomiting, it is recommended that patients go to the regular hospital in a timely manner, after the cause of the disease is clear, under the guidance of the doctor for targeted treatment.