Leg bend tenderness generally refers to pain in the tissues around the knee joint and should be treated with general therapy, medication, physical therapy and surgery depending on the cause. Common causes include physiologic pain, trauma, knee osteoarthritis, degenerative diseases of lumbar vertebrae and so on. 1. Physiological pain: If the lower limbs are over-exercised, it can cause lactic acid accumulation in the muscles around the knee joint, resulting in pain in the big tendon of the leg bend, which can be relieved after resting in general. 2. Trauma: Trauma caused by knee ligaments, muscles and other tissue damage, if the damage is mild, the knee can be used to brake and rest, early cold compresses, when the pain is serious, you can use celecoxib and other drugs to relieve pain. If the damage is more serious, surgical treatment can be taken, such as ligament reconstruction surgery, rehabilitation exercises during the recovery period. 3. Knee osteoarthritis: For knee osteoarthritis caused by hamstring pain, should avoid excessive weight bearing, line hot compresses and other physical therapy, the use of pain relieving drugs such as Loxoprofen sodium treatment. Conservative treatment is ineffective when the feasible surgical treatment, such as knee arthroplasty. 4. Lumbar degenerative diseases: for lumbar degenerative diseases such as lumbar disc herniation, lumbar spondylolisthesis and other diseases caused by hamstring pain, oral celecoxib and other non-steroidal drugs, as well as methylcobalamin and other nutritive nerve medications for treatment. It is also feasible to apply hot compresses, baking electricity and other physical therapy. Conservative treatment is ineffective or when symptoms worsen, surgical treatment is feasible, such as lumbar spine minimally invasive nucleus pulposus removal surgery. There are other causes of hamstring pain, if not relieved after rest, you should go to the hospital in a timely manner to improve the examination, to clarify the cause of the targeted treatment in accordance with the doctor’s instructions, do not self-medication, so as not to delay the condition.