Increased thyrotropin receptor antibody (TRAb) is often seen in Graves’ disease, but also in other diseases such as Hashimoto’s thyroiditis, which need to be combined with thyroid hormones and other indicators to clarify the diagnosis. 1. Graves’ disease: If the patient has hyperthyroidism, a positive TRAb is an important marker for the diagnosis of Graves’ disease, and can distinguish it from hyperthyroidism caused by other etiologies. Detection of TRAb is helpful in evaluating the efficacy of treatment. Continued treatment with low-dose antithyroid medication until TRAb becomes negative can reduce the recurrence rate of Graves’ disease. 2. Hashimoto’s thyroiditis: TRAb may also be elevated in patients with Hashimoto’s thyroiditis, especially when combined with hyperthyroidism. However, it is generally lower than in Graves’ disease and is less common. If you find high thyroid hormone receptor antibodies in your body, it is recommended that you improve your thyroid hormone tests and combine them with the patient’s clinical symptoms for diagnosis and treatment.