Whether or not surgery is needed for isthmic vertebral body slippage 1 degree should be judged according to the severity of the specific condition. If the patient’s symptoms are not obvious, surgery may not be needed, and if the patient’s symptoms are more serious, surgery will be needed. Isthmus vertebral body slippage 1 degree is the spine between the upper and lower articular process of the bone cortex fracture, resulting in lumbar pain symptoms, if the patient does not have obvious symptoms or symptoms are mild, can be conservative treatment, such as lumbar wear support, ultrashort-wave therapy, microwave therapy, etc., usually to strengthen the lumbar back muscle muscle strength training, most of the patients’ symptoms can be relieved. If the patient has serious clinical symptoms, such as severe pain in the lumbar region, weakness of the lower limbs and other symptoms, it is necessary to consider surgical treatment, such as intervertebral fusion, decompression of the spinal canal, pedicle internal fixation nails and other treatments, which can stabilize the spinal column and relieve the symptoms of pain. Isthmus vertebral body slipped 1 degree should be timely to the hospital, follow the doctor’s instructions combined with their own situation for reasonable treatment, so as not to delay the condition.