Appendicitis with abscess should be actively anti-infective treatment, as well as surgical treatment and other measures. Appendicitis with abscess may be acute suppurative appendicitis, which is likely to cause swelling of the appendix, covered with purulent exudate, and severe limited peritonitis, with serious clinical signs and symptoms, and also cause severe abdominal pain, high fever, and fatigue. Clinically, the following treatments are mainly given: 1. Anti-infective treatment: acute inflammation should be timely intravenous drip sensitive, potent antibiotics into anti-infective treatment, you can choose ceftriaxone sodium, levofloxacin, ornidazole and other antibiotic treatment. 2. Surgery: appendectomy is usually required. If pus is formed in the abdominal cavity, it should be changed to caesarean section combined with appendectomy, and the abdominal cavity needs to be irrigated during the operation to suck out the pus and then close the abdomen. Care should be taken to protect the incision with one-stage sutures, and appendectomy can also be performed laparoscopically. Appendicitis with abscess should go to the regular hospital surgery in time, follow the doctor’s instructions for treatment, and pay close attention to observation.