Numbness of hands and feet four months after chemotherapy for colon cancer is mainly seen in peripheral nerve damage caused by chemotherapeutic drugs, and the symptoms can be relieved by the following aspects: 1. Drugs such as methylcobalamin and vitamin B6 can be taken to repair the damaged nerves and promote the improvement of symptoms. 2. You can wear ice gloves before chemotherapy to reduce the running of drugs to hands and feet; after chemotherapy, pay attention to keep warm and reduce hot and cold stimulation. 3. If there is no significant improvement in symptoms through the above methods, and if the quality of life is seriously affected, chemotherapy drugs can be changed to alleviate the symptoms under the advice of the doctor. Generally speaking, if the neurological damage caused by chemotherapy is relatively mild, it will gradually improve on its own or even disappear completely with the extension of time after the end of chemotherapy. Due to individual differences, the severity of symptoms varies, it is recommended to use medication and care under the guidance of a doctor.