Helicobacter pylori infection needs to be treated with quadruple therapy under a doctor’s supervision, i.e., two antibiotics combined with bismuth and proton pump inhibitors; the price of the drug will vary according to the type of drug and the geographical area of the manufacturer, such as amoxicillin ranging in price from $7 to $35, and levofloxacin ranging in price from $5 to $50. Infection with Helicobacter pylori is usually often considered to be treated with quadruple therapy, i.e. two antibiotics combined with bismuth and proton pump inhibitors; the composition of antibiotics may include amoxicillin + clarithromycin, amoxicillin + levofloxacin, etc.; proton pump inhibitors include omeprazole, pantoprazole, etc.; bismuth includes bismuth potassium citrate, colloidal bismuth pectin, etc.. The prices corresponding to different drugs will vary somewhat. The price of amoxicillin ranges from $7 to $35, levofloxacin from $5 to $50, omeprazole from $3 to $120, pantoprazole from $6 to $130, and bismuth potassium citrate from $18 to $48. People with H. pylori infection who need to use medication are advised to use the medication under a doctor’s supervision; the price of the medication can vary greatly, so please refer to the specific situation.